Table 3.

Parameters of drug-induced baroreflex sensitivity analyses

	Wild-type (n = 6)		Cry1−/−Cry2−/− (n = 5)
	Day	Night	Day	Night
Gain (beats min−1 mmHg−1)	−17.4 ± 2.0	−32.1 ± 3.9**	−41.1 ± 3.2***	−40.6 ± 1.4***
Minimum (beats min−1)	323 ± 10	323 ± 14	358 ± 25	346 ± 10
Maximum (beats min−1)	607 ± 25	698 ± 26***	752 ± 28**	734 ± 21**
Saturation (mmHg)	93.4 ± 2.1	96.2 ± 2.1	101.6 ± 4.2	99.4 ± 2.0
Threshold (mmHg)	68.6 ± 2.5	77.8 ± 1.8***	86.8 ± 4.0**	85.0 ± 1.7***
Midpoint (mmHg)	81.0 ± 2.3	87.0 ± 1.8***	94.2 ± 4.0*	92.2 ± 1.8**

Values are means ± s.e.m. Significant differences from wild-type mice in the day:

^*P < 0.05

^**P < 0.01

^***P < 0.001.

Parameters that were used to develop the baroreflex curves in Fig. 3B are shown.