Table 2.
Genes of the CB up-regulated or down-regulated in response to 10% O2 hypoxia for 24 h
| Probe set ID | Gene Title | Gene Symbol | Fold | P-value |
|---|---|---|---|---|
| Concordant 2.5-fold increase P-value < 0.001 | ||||
| 1438211_s_at | D site albumin promoter binding protein | Dbp | 13.03 | 0.000021 |
| 1448276_at | transmembrane 4 superfamily member 7 | Tm4sf7 | 7.09 | 0.000020 |
| 1451185_at | Splicing factor 3b, subunit 5 | 1110005L13Rik | 6.31 | 0.000721 |
| 1451208_at | eukaryotic translation termination factor 1 | Etf1 | 5.84 | 0.000892 |
| 1427747_a_at | lipocalin 2 | Lcn2 | 5.78 | 0.000085 |
| 1428942_at | metallothionein 2 | Mt2 | 5.36 | 0.000020 |
| 1422185_a_at | diaphorase 1 (NADH) | Dia1 | 4.66 | 0.000020 |
| 1449036_at | ring finger protein 128 | Rnf128 | 4.59 | 0.000148 |
| 1422557_s_at | metallothionein 1 | Mt1 | 4.21 | 0.000020 |
| 1423145_a_at | titin-cap | Tcap | 4.04 | 0.000020 |
| 1452777_a_at | NUB1, a NEDD8-interacting protein | 6330412F12Rik | 4.03 | 0.000669 |
| 1449525_at | flavin containing monooxygenase 3 | Fmo3 | 3.91 | 0.000027 |
| 1426464_at | nuclear receptor subfamily 1, group D, member 1 | Nr1d1 | 3.84 | 0.000098 |
| 1449851_at | period homolog 1 (Drosophila) | Per1 | 3.77 | 0.000129 |
| 1418318_at | ring finger protein 128 | Rnf128 | 3.13 | 0.000148 |
| 1435386_at | Von Willebrand factor homolog | Vwf | 3.07 | 0.000020 |
| 1418936_at | v-maf musculoaponeurotic fibrosarcoma oncogene, protein F | Maff | 3.07 | 0.000020 |
| 1448181_at | Kruppel-like factor 15 | Klf15 | 2.92 | 0.000036 |
| 1442025_a_at | expressed sequence AI467657 | AI467657 | 2.91 | 0.000037 |
| 1418025_at | basic helix-loop-helix domain containing, class B2 | Bhlhb2 | 2.83 | 0.000094 |
| 1453678_at | methyl-CpG binding domain protein 1 | Mbd1 | 2.79 | 0.000512 |
| 1428955_x_at | solute carrier family 9, isoform 3 regulator 2 | Slc9a3r2 | 2.78 | 0.000021 |
| 1451121_a_at | glioma tumour suppressor candidate region gene 2 | Gltscr2 | 2.74 | 0.000037 |
| 1418296_at | FXYD domain-containing ion transport regulator 5 | Fxyd5 | 2.72 | 0.000020 |
| 1432466_a_at | apolipoprotein E | Apoe | 2.71 | 0.000024 |
| 1426383_at | cryptochrome 2 (photolyase-like) | Cry2 | 2.70 | 0.000033 |
| 1436046_x_at | ribosomal protein L29 | Rpl29 | 2.68 | 0.000036 |
| 1448839_at | DNA segment, Chr 17, ERATO Doi 288, | D17Ertd288e | 2.66 | 0.000168 |
| 1449461_at | retinol binding protein 7, cellular | Rbp7 | 2.63 | 0.000250 |
| 1419674_a_at | dipeptidase 1 (renal) | Dpep1 | 2.63 | 0.000026 |
| 1416125_at | FK506 binding protein 5 | Fkbp5 | 2.61 | 0.000666 |
| 1451130_at | RIKEN cDNA 2010315L10 gene | 2010315L10Rik | 2.61 | 0.000020 |
| 1448862_at | intercellular adhesion molecule 2 | Icam2 | 2.60 | 0.000020 |
| 1419874_x_at | zinc finger protein 145 | Zfp145 | 2.58 | 0.000338 |
| 1428538_s_at | retinoic acid receptor responder (tazarotene induced) 2 | Rarres2 | 2.56 | 0.000543 |
| 1423233_at | CCAAT/enhancer binding protein (C/EBP), delta | Cebpd | 2.56 | 0.000020 |
| 1436586_x_at | ribosomal protein S14 | Rps14 | 2.52 | 0.000023 |
| 1452674_a_at | RIKEN cDNA 1200009C21 gene (eIF-3 p25) | 1200009C21Rik | 2.52 | 0.000020 |
| Concordant 2.5-fold decrease P-value < 0.001 | ||||
| 1420465_s_at | major urinary protein 1 | Mup1 | −9.83 | 0.000020 |
| 1450779_at | fatty acid binding protein 7, brain | Fabp7 | −4.91 | 0.000049 |
| 1427884_at | procollagen, type III, alpha 1 | Col3a1 | −3.49 | 0.000023 |
| 1420855_at | elastin | Eln | −3.10 | 0.000020 |
| 1425425_a_at | Wnt inhibitory factor 1 | Wif1 | −3.09 | 0.000073 |
| 1448755_at | procollagen, type XV | Col15a1 | −2.89 | 0.000202 |
| 1424556_at | pyrroline-5-carboxylate reductase 1 | Pycr1 | −2.79 | 0.000113 |
| 1422789_at | aldehyde dehydrogenase family 1, subfamily A2 | Aldh1a2 | −2.78 | 0.000767 |
| 1417403_at | ELOVL family member 6 | Elovl6 | −2.74 | 0.000201 |
| 1420725_at | trimethyllysine hydroxylase, epsilon | Tmlhe | −2.70 | 0.000022 |
| 1426460_a_at | UDP-glucose pyrophosphorylase 2 | Ugp2 | −2.60 | 0.000569 |
| 1419519_at | insulin-like gth factor 1 | Igf1 | −2.57 | 0.000046 |
| 1418937_at | deiodinase, iodothyronine, type II | Dio2 | −2.51 | 0.000025 |
The genes selected for the table are the ones that show consistent (equivalent change calls), > 2.5-fold, and significant (P < 0.001) changes in transcription.