Table 4.
FACS analysis
|
CFC assay % GFP§
|
|||
---|---|---|---|---|
%hCD45* | % GFP† | P‡ | ||
-cyt | 28 ± 14 | 54 ± 20 | .029∥ | 39 ± 14 |
+cyt | 42 ± 32 | 91 ± 5 | 68 ± 15 | |
-cyt Ara-C | 23 ± 22 | 29 ± 8 | .028¶ | 18 ± 13 |
+cyt Ara-C | 7 ± 6 | 61 ± 22 | 45 ± 22 |
All values are expressed as mean ± SD of 2 experiments performed. For -cyt group, n = 4; for +cyt group, n = 4; for -cyt Ara-C group, n = 6; and for +cyt Ara-C group, n = 5.
n indicates number of mice per group.
Percentage of human cells in the mouse BM.
Percentage of human GFP-expressing cells.
P value calculated by rank sum 2-sided test.
Percentage of human GFP-expressing cells, scored by fluorescence microscopy.
-cyt versus +cyt.
-cyt Ara-C versus +cyt Ara-C.