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. 2006 Feb 9;107(11):4257–4265. doi: 10.1182/blood-2005-10-4047

Table 4.

S-phase suicide assay: SRC analysis

FACS analysis
CFC assay % GFP§
%hCD45* % GFP P
-cyt 28 ± 14 54 ± 20 .029 39 ± 14
+cyt 42 ± 32 91 ± 5 68 ± 15
-cyt Ara-C 23 ± 22 29 ± 8 .028 18 ± 13
+cyt Ara-C 7 ± 6 61 ± 22 45 ± 22

All values are expressed as mean ± SD of 2 experiments performed. For -cyt group, n = 4; for +cyt group, n = 4; for -cyt Ara-C group, n = 6; and for +cyt Ara-C group, n = 5.

n indicates number of mice per group.

*

Percentage of human cells in the mouse BM.

Percentage of human GFP-expressing cells.

P value calculated by rank sum 2-sided test.

§

Percentage of human GFP-expressing cells, scored by fluorescence microscopy.

-cyt versus +cyt.

-cyt Ara-C versus +cyt Ara-C.