. 2006 Feb 7;107(11):4338–4345. doi: 10.1182/blood-2005-12-5021

Table 1.

Increased numbers of HSC cells in the BM and spleen of SHIP^-/- mice compared with WT littermates

	Increase in WBM cells, %			Absolute no. cells per pair of femur and tiba
Population	SHIP^-/-	WT	P	SHIP^-/-	WT	P
Lin^-Sca1⁺cKit⁺Thy1^low
BM	0.4114 ± 0.0353	0.0725 ± 0.025	< .001	(20.53 ± 3.39) × 10⁴	(3.79 ± 1.53) × 10⁴	.001
Spleen	0.0957 ± 0.0131	0.0142 ± 0.0040	.004	(50.90 ± 9.25) × 10³	(5.80 ± 1.92) × 10³	.009
Lin^-Sca1⁺cKit⁺Flk2^-
BM	0.2860 ± 0.0398	0.1340 ± 0.0202	.009	(22.14 ± 4.59) × 10⁴	(10.3 ± 7.22) × 10⁴	.034
Spleen	0.0827 ± 0.0141	0.027 ± 0.002	.017	(52.10 ± 7.89) × 10³	(13.58 ± 0.75) × 10³	.008
Lin^-Sca1⁺cKit⁺CD48^-
BM	0.019 ± 0.002	0.0068 ± 0.0006	.001	(7.84 ± 0.95) × 10³	(2.76 ± 0.30) × 10³	< .001
Spleen	0.0020 ± 0.0003	0.00023 ± 0.00005	.005	(55.3 ± 0.73) × 10²	(2.89 ± 0.87) × 10²	.002
Lin^-Sca1⁺cKit⁺CD48^-CD150⁺
BM	0.00084 ± 0.00001	0.0004 ± 0.0001	.039	(3.5 ± 0.19) × 10²	(1.64 ± 0.62) × 10²	.045
Side population
BM	0.0565 ± 0.0044	0.0290 ± 0.0044	.005	(26.7 ± 4.7) × 10³	(12.5 ± 2.4) × 10³	.035

At least 3 mice were tested for each genotype.