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Mammalian ARE-containing mRNAs contain candidate binding sites for CUG-BP. The sequences of c-fos and TNFα RNA substrates are depicted, with AU-rich elements and putative CUG-BP binding sites highlighted. In addition, the region of the c-fos RNA with the best matches to CUG-BP consensus is labeled (A). The sequence of the EDEN region of c-mos, which is used as a competitor in Figure 3, is also shown.
