FIGURE 8.
A pre-tRNA can be divided into five parts, each of them expected to contribute differently to tRNase Z recognition and catalysis. (A) The T arm; (B) acceptor stem; (C) tRNase Z processing site; (D) three nucleotides following the cleavage site (xxx = CCA of mature tRNA or “not-CCA” of a pre-tRNA); (E) additional sequence of the 3′-end trailer.