. 2004 May;2(3):267–273. doi: 10.1370/afm.21

Table 4.

Probably Ineffective Nonsurgical Treatment of Carpal Tunnel Syndrome

Treatment	Evidence	Findings
NSAID	2 RCTs^16,¹⁸	No significant reduction in symptom measures
Diuretic	1 RCT¹⁶	No significant reduction in symptom measures from baseline to 4^th week assessment
Pyridoxine	2 RCTs^27,²⁸	Reduced finger swelling and discomfort after movement but no difference in nocturnal pain, numbness, Phalen’s or Tinel’s signs or nerve conduction studies in one study, and no significant difference in the other study
Chiropractic treatment	1 RCT¹⁸	No significant reduction in symptom measures
Magnet therapy	1 RCT¹⁵	No difference in effect between magnet and placebo

NSAID = nonsteriodal anti-inflammatory drug; RCT = randomized controlled trial.