. Author manuscript; available in PMC: 2006 May 24.

Published in final edited form as: J Comb Chem. 2004;6(3):437–442. doi: 10.1021/cc0340473

Table 1.

IC50 values of the four most active compounds and CQ against the 3D7, W2 and Dd2 P. falciparum strains. Values are expressed as nM. These studies were run at a higher parasitemia than the screening studies in order to provide a more stringent test of activity thus leading to slightly elevated

	Strains
Compound	3D7	W2	Dd2
CQ	25	>250	>250
1{2,16}	45	45	45
1{2, 21}	50	70	45
1{2, 22}	50	50	45
1{13, 23}	50	130	150