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Comparison of enzymatic properties of IPP isomerases
| Monomer, kDa | Km (for IPP), μM | kcat (for IPP), s−1 | kcat/Km, M−1⋅s−1 | Divalent cation | FMN-dependence | NAD(P)H-dependence | Reference | |
|---|---|---|---|---|---|---|---|---|
| Streptomyces sp. CL190 | 41 | 450 | 0.70 | 1.6 × 103 | Mg2+ | yes | yes | This study |
| S. aureus | 39 | 19 | 1.3 | 6.8 × 104 | Mg2+ | yes | yes | This study |
| E. coli | 25 | 7.9 | 0.33 | 4.2 × 104 | Mg2+ | no | no | 22 |
| S. cerevisiae | 26 | 43 | 8.0 | 1.9 × 105 | Mg2+ | no | no | 21 |
| Human | 39 | 33 | 1.8 | 5.5 × 104 | Mg2+ | no | no | 20 |
