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Effect of supercoiling on the juxtaposition time. Computed dependencies of 〈τc〉 on σ correspond to 0.2 M (●) and 0.01 M (○) monovalent ions. Data were obtained for 3-kb DNA and 600-bp separations between the chosen sites along the chain contour. Typical simulated conformations of supercoiled DNA (σ = −0.06, 0.2 M (blue) and 0.01 M (red) concentration of monovalent salt ions) and relaxed DNA (green) are also shown. For σ = 0, conformations depend weakly on ionic conditions.
