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. 2006 Jan;96(1):114–119. doi: 10.2105/AJPH.2004.056796

TABLE 2—

Cost-Effectiveness and Sensitivity Analyses Without Free VCT, With a Free VCT Campaign, and With Sustained Free VCT

No Free VCT Free VCT Campaign Sustained Free VCT
Number Treated New Diagnoses Infections Averted Cost Per Infection Averteda DALYs Gained Cost Per DALY, US $ Number Treated New Diagnoses Infections Averted Cost Per Infection Averted DALYs Gained Cost Per DALY, US $ Number Treated New Diagnoses Infections Averted Cost Per Infection Averted DALYs Gained Cost Per DALY, US $
Prevention
HIV prevalence
    Observed (16.7%) . . . . . . 67.9 169.69 1321 8.72 . . . . . . 131.0 105.12 2549 5.40 . . . . . . 275.0 91.89 5352 4.72
    Low (8%) . . . . . . 40.0 288.04 778 14.80 . . . . . . 77.2 178.47 1502 9.17 . . . . . . 162.0 156.00 3152 8.02
    High (25%) . . . . . . 95.0 121.24 1848 6.23 . . . . . . 183.3 75.12 3567 3.86 . . . . . . 384.9 65.66 7490 3.37
New diagnoses
HIV prevalence
    Observed (16.7%) . . . 161.4 . . . . . . . . . . . . . . . 311.3 . . . . . . . . . . . . . . . 653.8 . . . . . . . . . . . .
    Low (8%) . . . 77.3 . . . . . . . . . . . . . . . 149.1 . . . . . . . . . . . . . . . 313.2 . . . . . . . . . . . .
    High (25%) . . . 241.5 . . . . . . . . . . . . . . . 466.0 . . . . . . . . . . . . . . . 978.8 . . . . . . . . . . . .
Antiretroviral treatmentb
Rates of treatment
    Medium (30%) 48.4 . . . . . . . . . 48.4 420.00c 93.4 . . . . . . . . . 93.4 420.00 196.1 . . . . . . . . . 196.1 420.00
    Low (10%) 16.1 . . . . . . . . . 16.1 420.00c 31.1 . . . . . . . . . 31.1 420.00 65.4 . . . . . . . . . 65.4 420.00
    High (50%) 80.7 . . . . . . . . . 80.7 420.00c 155.6 . . . . . . . . . 155.6 420.00 326.9 . . . . . . . . . 326.9 420.00
Tuberculosis prophylaxisb
Rates of treatment
    Medium (50%) 80.7 . . . . . . . . . 12.1 166.67d 155.6 . . . . . . . . . 23.3 166.67 326.9 . . . . . . . . . 49.0 166.67
    Low (30%) 48.4 . . . . . . . . . 7.3 166.67d 93.4 . . . . . . . . . 14.0 166.67 196.1 . . . . . . . . . 29.4 166.67
    High (70%) 112.9 . . . . . . . . . 16.9 166.67d 217.9 . . . . . . . . . 32.7 166.67 457.7 . . . . . . . . . 68.6 166.67
Summaryb
Scenario
    Medium treatment . . . . . . . . . . . . 1381.4 24.52 . . . . . . . . . . . . 2666.0 21.34 . . . . . . . . . . . . 5,597.2 20.69
    Low treatment . . . . . . . . . . . . 1344.3 14.51 . . . . . . . . . . . . 2594.4 11.25 . . . . . . . . . . . . 5,446.9 10.58
    High treatment . . . . . . . . . . . . 1418.5 34.00 . . . . . . . . . . . . 2737.6 30.90 . . . . . . . . . . . . 5,747.6 30.28

Note. VCT = voluntary counseling and testing; DALY = disability-adjusted life year.

aBased on previous estimates in Tanzania.2

b With an observed HIV infection prevalence of 16.7%.

cAssumes cost for antiretroviral therapy of $35 per month and does not include cost for monitoring and care.

dBased on an estimated cost of $25 for 6 months of preventive therapy.15