TABLE 2—

Backward Stepwise Proportional Hazard Models for Smoking and Prognosis after Highly Active Antiretroviral Therapy

	Hazards Ratio (95% CI)	P
Viral response (n = 863; 551 events)
Age	1.009 (1.003, 1.014)	.002
Smoker	0.79 (0.67, 0.93)	.006
ART naïve	2.18 (1.75, 2.71)	.001
Log viral load	0.84 (0.81, 0.87)	.001
Viral rebound (n = 524; 333 events)
Smoker	1.39 (1.06, 1.69)	.013
Hispanic vs White	1.29 (0.56, 0.99)	.04
Illicit drug use	1.56 (1.13, 2.07)	.007
ART naïve	0.73 (0.55, 0.99)	.034
Log viral load	1.06 (1.01, 1.11)	.01
Immunologic response (n = 863; 678 events)
Smoker	0.85 (0.73, 0.99)	.041
Hispanic vs White	0.79 (0.66, 0.96)	.016
Log CD4+ count	1.33 (1.22, 1.44)	.001
Immunologic failure (n = 660; 261 events)
Smoker	1.52 (1.18, 1.96)	.001
Hispanic vs White	1.49 (1.12, 1.97)	.006
Log CD4+ count	1.49 (1.27, 1.74)	.001
AIDS incidence (n = 841; 343 events)
Smoker	1.36 (1.07, 1.72)	.011
Illicit drug use	1.74 (1.32, 2.30)	.001
Prior AIDS	2.30 (1.83, 2.88)	.001
Log CD4+ count	0.80 (0.73, 0.87)	.001
Log viral load	1.07 (1.02, 1.13)	.004
Total deaths (n = 863; 151 events)
Age	1.02 (1.01, 1.03)	.006
Smoker	1.53 (1.08, 2.19)	.018
HCV	2.05 (1.45, 2.88)	0.001
ART naïve	0.43 (0.25, 0.76)	.003
Log CD4+ count	0.62 (0.55, 0.70)	0.001
Log viral load	1.09 (1.01, 1.18)	0.023
Death from AIDS (n = 863; 63 events)
HCV	2.03 (1.23, 3.35)	0.005
ART naïve	0.41 (0.18, 0.96)	0.04
Log CD4+ count	0.56 (0.48, 0.67)	0.001
Log viral load	1.28 (1.11, 1.47)	.001

Note. ART = antiretroviral therapy; HCV = hepatitis C virus.