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Immunohistochemical analysis of COX-1 and COX-2. DA sections obtained from neonates sacrificed 2.5 h after birth. (A) COX-1(+/+)/COX-2(+/+), anti-COX-2; (Inset) perinuclear staining. (B) COX-1(+/+)/COX-2(−/−), anti-COX-2. (C) COX-1(+/+)/COX-2(+/+), anti-COX-1; (Inset) epidermis of COX-1(+/+)/COX-2(+/+), anti-COX-1. (Scale bar, 100 μm.) Genotype figure labels, Ptgs1 genotype/Ptgs2 genotype.
