Fig. 1: Risk ratios for the composite outcome (death, stroke or myocardial infarction) for (A) patients less than 60 years of age and (B) patients 60 years of age and older receiving β-blockers or placebo. The size of the boxes represents the number of participants who experienced a cardiovascular event. The mean age of trial participants is given in parentheses after each trial acronym. Trials are listed in order of publication. CI = confidence interval.