Table 2.
Hazard ratios (95% confidence intervals) of coronary heart disease according to drinking frequency among women and men
Variable
|
Frequency of drinking alcohol (days/week)
|
P for trend*
|
|||||
---|---|---|---|---|---|---|---|
Never | <1 | 1 | 2-4 | 5 or 6 | 7 | ||
Women: | |||||||
No of cases | 24 | 276 | 95 | 187 | 77 | 90 | |
Adjusted for age | 1.01 (0.66 to 1.53) | 1.00 | 0.60 (0.47 to 0.76) | 0.56 (0.47 to 0.68) | 0.69 (0.54 to 0.89) | 0.62 (0.49 to 0.79) | 0.0004 |
Adjusted for multiple factors† | 0.92 (0.61 to 1.41) | 1.00 | 0.64 (0.51 to 0.81) | 0.63 (0.52 to 0.77) | 0.79 (0.61 to 1.03) | 0.65 (0.51 to 0.84) | 0.007‡ |
Men: | |||||||
No of cases | 39 | 180 | 140 | 424 | 195 | 305 | |
Adjusted for age | 1.38 (0.98 to 1.95) | 1.00 | 0.86 (0.69 to 1.07) | 0.69 (0.58 to 0.83) | 0.65 (0.53 to 0.79) | 0.60 (0.50 to 0.73) | <0.0001 |
Adjusted for multiple factors† | 1.44 (1.02 to 2.04) | 1.00 | 0.93 (0.75 to 1.16) | 0.78 (0.66 to 0.94) | 0.71 (0.57 to 0.87) | 0.59 (0.48 to 0.71) | <0.0001 |
Never drinkers not included in analyses for trend.
Age, smoking, education, physical activity, body mass index, total intake of fruit, vegetables, fish, and saturated fat.
P for trend was 0.49 when women were excluded who never drink or drink on less than one day a week.