FIG. 2.

CCL2 expression reflects the immunopathological response to RSV infection. (A) Levels of CCL2 mRNA were assessed by RNase protection assays in whole lungs of BALB/c or C57BL/6 mice 24 h following RSV infection. Each mouse was tested individually (n = 4 per group). Some mice had been primed 2 to 3 weeks earlier with either rVV-F, rVV-G, or the control rVV-βgal. Results are expressed as protected band intensity and are percentages of the intensity of the housekeeping genes L32 and GAPDH. (B) In similar experiments, CCL2 protein levels were assessed in cell-free BAL fluids by ELISAs at different time points following RSV infection. *, P < 0.05 for comparison of rVV-G- and rVV-F-primed BALB/c mice.