. 2006 May;80(10):4949–4961. doi: 10.1128/JVI.80.10.4949-4961.2006

TABLE 5.

Percentages of CD4⁺ CD44^high and CD8⁺ CD44^high T cells obtained from the spleens of mock-, VP6/LT(R192G)-, and RRV-immunized neonatal or adult mice that were stimulated to produce cytokines at 10 or 28 dpi, as determined by fluorescence-activated cell sorting^a

Age at immunization	Immunization protocol	Time (dpi)	% of CD4⁺ CD44^high cells with cytokine			% of CD8⁺ CD44^high cells with cytokine
Age at immunization	Immunization protocol	Time (dpi)	IL-2	IL-17	IFN-γ	IL-17	IFN-γ
Neonate	Mock^b	10	—^d	—	—	—	—
	VP6/LT(R192G)^b	10	—	—	—	—	—
	RRV^c	10	—	—	—	—	—
	Mock^b	28	—	—	—	—	—
	VP6/LT(R192G)^b	28	0.10	0.34	0.16	—	0.40
	RRV^c	28	—	—	0.12	—	0.60
Adult	Mock^b	10	—	—	—	—	—
	VP6/LT(R192G)^b	10	0.36	0.35	.013	—	0.54
	RRV^c	10	—	—	—	—	—
	Mock^b	28	—	—	—	—	—
	VP6/LT(R192G)^b	28	0.53	0.33	—	—	1.50
	RRV^c	28	—	—	0.33	—	0.53

Values represent percentages of cells stained in stimulated cultures minus those stained in unstimulated cultures.

Cultures were stimulated with 4 μg of EDIM VP6::6XHis.

Cultures were stimulated with 10 μg of purified RRV particles.

—, values of <0.1%.