TABLE 3.
Subject (HLA) and response | Fold change from baseline
|
|||
---|---|---|---|---|
CD45RA+ CCR7− | CD45RA+ CCR7+ | CD45RA− CCR7+ | CD45RA− CCR7− | |
012b (B7), Nef | 0 | 0.53 | 12 | 7.8 |
012b (B8), p24 | 5 | 2.46 | 17.8 | 9.2 |
012b (A3), Nef | 1.98 | 1.2 | 14.1 | 5.6 |
013 (B8), p24 | 0 | 3.4 | 18.6 | 10.2 |
015 (B27), p24 | 2.2 | 10.4 | 11.4 | 14.6 |
021 (B8), Nef | 2.2 | 0.14 | 7.3 | 6.3 |
004 (A3), Pol | 3.68 | 1.54 | 18.15 | 6.5 |
Compartments within tetramer-positive populations were defined as shown in Fig. 2C. Fold changes from preimmunization values were calculated after adjusting for the number of CD8+ lymphocytes acquired (typically 2 × 105).
Postvaccination analysis for subject 012 was performed on the 12-month sample.