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Infection studies with KoRV. (a) Detection of provirus in different cell lines before and after infection with KoRV using PCR. PBMCs from a healthy koala were taken as the positive control. (b) Fifty percent tissue culture infective dose (TCID50) values (means and standard deviations) of KoRV produced from different cell lines and titrated on human 293 cells. (c) Transmission electron microscopy of KoRV produced by human 293 kidney cells and (d) KoRV particles in koala lymphoma cells.
