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Changes in body weight, MPXV loads in total peripheral blood, and cytokine responses. (A) Body weight expressed as a percentage of that measured at the time of MPXV challenge. (B) Viral loads in total peripheral blood as measured by qPCR. (C) IFN-γ response. (D) IL-6 response. Left and right panels show these indicators for monkeys challenged intranasally with MPXV strain Liberia and subcutaneously with MPXV Zr-599, respectively.
