TABLE 3.
Activity of levofloxacin against strains of P. aeruginosa in a systemic infection model
| Strain | MIC (μg/ml) | ED50 (μg/kg) | 95% confidence limit | ED50/MIC ratio |
|---|---|---|---|---|
| PAM 1154 | 0.015 | 2.4 | 1.5-3.3 | 160 |
| PAM 1626 | 0.015 | 1.4 | 0.6-2.2 | 93.3 |
| PAM 1020 | 0.25 | 13.6 | 8.0-20 | 54.4 |
| PAM 1409 | 0.25 | 10.6 | 5.0-16 | 42.4 |
| PAM 1623 | 0.25 | 15.1 | 7.0-23 | 60.4 |
| PAM 1032 | 1.50 | 65.6 | 32-97 | 43.7 |
| PAM 1723 | 1.50 | 63.2 | 46-79 | 42.1 |
| PAM 1033 | 2.25 | 100.4 | 76-142 | 44.6 |
| PAM 1177 | 1.00 | 38.2 | 24-53 | 38.2 |
| PAM 1034 | 4.00 | 64.4 | 48-81 | 16.1 |
| PAM 1168 | 3.25 | 33.2 | 19-47 | 10.2 |
| PAM 1001 | 3.25 | 24.1 | 16-33 | 6.0 |
| PAM 1014 | 3.25 | 15.1 | 3.0-27 | 3.8 |