. 2006 May;50(5):1823–1827. doi: 10.1128/AAC.50.5.1823-1827.2006

TABLE 1.

Comparative efficacies of EDTA alone and in combination with amphotericin B preparations in the treatment of invasive pulmonary aspergillosis in severely immunocompromised rats

Group	Total no. of rats	Mean log₁₀ no. of CFU/g of lung (range) (no. of rats)		Angioinvasive lung lesion histopathology grade (range)
Group	Total no. of rats	At 7 days	From rats surviving >7 days	Angioinvasive lung lesion histopathology grade (range)
Control	16	3.65 (2.93-4.26) (12)	3.46 (3.32-3.83) (4)	3+ (2+-4+)
AMB	16	2.29 (0-3.68) (8)	0.61 (0-2.3) (8)	3+ (0+-3+)
ABLC	16	1.65 (0-3.46) (7)	0.67 (0-2.8) (9)	2+ (2+-4+)
EDTA	16	2.27 (0-3.75) (7)	1.0 (0-3.3) (9)	3+ (0+-3+)
ABLC + EDTA	16	0.45 (0-1.7) (7)	0.25 (0-1.8) (9)	0+ (0+-2+)