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Schematic representation of PfNDH2 function in the P. falciparum mitochondrial ETC. The exact location of PfNDH2 is not known; in the schematic it is shown as localized on either the cytosolic (a) or the matrix (b) side of the mitochondrial inner membrane. Inhibition of PfNDH2 and the bc1 complex (lighting bolts) has been shown to be synergistic, probably by affecting the redox reactions of the Q cycle.
