TABLE 2.
P. falciparum growth inhibition by mitochondrial ETC inhibitorsa
| Drug | IC50 (μM) (n) |
|---|---|
| DPI | 0.24 ± 0.03 (10) |
| IDP | 5.99 ± 0.36 (8) |
| Rotenone | 27.02 ± 3.50 (4) |
| Flavone | 64.24 ± 2.00 (4) |
| Dicumarol | 113.78 ± 11.50 (4) |
| 5-FO | 0.031 ± 0.003 (5) |
| TTFA | 20.44 ± 2.26 (7) |
| 3-NP | 158.12 ± 11.20 (6) |
| Atovaquone | 0.001 ± 0.0002 (35) |
| Chloroquine | 0.080 ± 0.007 (2) |
Values are means ± standard deviations of results from independent experiments.