Table 3.

Cytokine profile in BALB/c mice that were treated with pCDR1 for the prevention of experimental SLE

Cytokine	Intracellular staining
	16/6Id,* %	16/6Id + pCDR1, %	16/6Id + reversed pCDR1, %
IL-2	100	47	115
INFγ	100	56	81
IL-4	100	100	98
IL-10	100	99	98

Cytokine profile was determined by intracellular staining of lymph node cells (see Materials and Methods) of mice killed 1 month after booster injection with the 16/6Id (≈2 weeks after treatment). The results are representative of two experiments (5–12% variations were observed between experiments). 

^*Staining of lymph node cells of mice immunized with 16/6Id was considered as 100% (100% stained cells = 2,650, 2,950, 2,300, and 1,550 for IL-2, INFγ, IL-4, and IL-10, respectively).