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Identification of a U-rich TDE in the 3′ UTR of Her-2 mRNA. (A) The firefly luciferase activity of the constructs containing 3′-end deletions and internal deletions is shown. (B) Northern analysis of the transiently expressed firefly luciferase RNA and the endogenous GAPDH RNA shows stable accumulation of all transcripts 72 h post-transfection. The sequence alignment of the 73-nt U-rich TDE across mammalian species is shown in C.
