TABLE 1.

Sequences and α-helicity of synthetic peptides

Peptide	Sequencea											[θ]222b	α-Helix (%)
Pep3	W	K	L	F	K	K	I	L	K	V	L-NH2	−9,048	23.5
BP01	W	K	L	F	K	K	I	L	K	V	L-OH	NDc	ND
BP02		K	L	F	K	K	I	L	K	K	L-NH2	ND	ND
BP03		K	L	F	K	K	I	L	K-NH2			ND	ND
BP04	W	K	L	F	K-NH2							ND	ND
BP05	W	K	L	F	K-OH							ND	ND
BP06						K	I	L	K	V	L-NH2	ND	ND
BP07						K	I	L	K	V	L-OH	ND	ND
BP08	Ac-W	K	L	F	K	K	I	L	K	V	L-NH2	−10,851	29.5
BP09	Ts-W	K	L	F	K	K	I	L	K	V	L-NH2	−13,341	37.8
BP10	Bz-W	K	L	F	K	K	I	L	K	V	L-NH2	−13,119	37.1
BP11	Bn-W	K	L	F	K	K	I	L	K	V	L-NH2	−10,665	28.9
BP12	Pam-W	K	L	F	K	K	I	L	K	V	L-NH2	ND	ND
BP13	F	K	L	F	K	K	I	L	K	V	L-NH2	ND	ND
BP14	Y	K	L	F	K	K	I	L	K	V	L-NH2	ND	ND
BP33	L	K	L	F	K	K	I	L	K	V	L-NH2	−8,918	23.1
BP15	K	K	L	F	K	K	I	L	K	V	L-NH2	−9,892	26.3
BP16	K	K	L	F	K	K	I	L	K	K	L-NH2	ND	ND
BP76	K	K	L	F	K	K	I	L	K	F	L-NH2	−9,188	24.0
BP17	W	K	L	F	K	K	I	L	K	K	L-NH2	ND	ND
BP18	W	K	L	F	K	K	I	L	K	W	L-NH2	−8,922	23.1
BP19	W	K	L	F	K	K	I	L	K	F	L-NH2	−9,950	26.5
BP20	W	K	L	F	K	K	I	L	K	Y	L-NH2	−10,316	27.7

^aBoldfaced letters indicate the modifications introduced into the Pep3 sequence. Ac, acetyl; Ts, tosyl; Bz, benzoyl; Bn, benzyl; Pam, palmitoyl.

^bDetermined in 50% trifluoroethanol in 10 mM sodium phosphate buffer (pH 7.4).

^cND, not determined.