Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model for evolution of CNV hotspots. Certain segmental duplications that arose in a human–chimpanzee common ancestor (depicted at point A) may facilitate separate nonallelic homologous recombination (NAHR) in both chimpanzees (B) and humans (C), leading to the genesis of CNVs in both species. If NAHR in these regions occurs frequently, it may be expected to lead to the maintenance of common CNVs by way of recurrent duplications and deletions.
