Table 4.

Comparison of clinical EAE courses in male and female progeny of B6 females × B6, B6.Y^A, and B6.Yaa male consomic mice elicited by using the double MOG_35–55 plus CFA induction protocol

Mice	Incidence			Clinical disease traits
	%	n		CDS	PS	DA	SI
B6	100	20		38.6	3.3	13.8	2.6
B6.YA	82	16		24.5	3.1	13.8	2.2
B6.Yaa	53	15		9.4	2.3	10.1	1.7
	χ2 11.9		F	21.1	5.9	12.1	8.6
	P 0.003		P	<10−3	0.006	<10−3	0.001
				CDS: B6 > B6.YA > B6.Yaa
				PS: B6 = B6.YA > B6.Yaa
				DA: B6 = B6.YA > B6.Yaa
				SI: B6 > B6.YA = B6.Yaa

CDS, mean cumulative disease score; PS, mean peak score; DA, mean days affected; SI, mean severity index.