Fig. 4.

Serum levels of hybrid κ/λ Ig. Serum hybrid κ/λ Ig levels were determined in κCκD and WT mice. Concentrations were relative to the optical density obtained by comparison with κDH mice (right) sera as control and were compared between transgenic κCκD mice (left) and WT controls (middle). Goat anti-mouse λ LC and goat anti-mouse κ LC were used at 2 and 1 μg/ml, respectively. The vertical axis is logarithmic. All ELISAs were performed on six different sera of each mouse strain.