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Titers of WT and mutant viruses in embryonated chicken eggs
| Virusa | Virus titer (PFU/ml)b |
|---|---|
| WT | |
| CCHH | (3.5 ± 0.2) × 108 |
| Double mutant | |
| ACAH | (7.5 ± 0.7) × 107 |
| Triple mutants | |
| CAAA | (3.7 ± 0.5) × 108 |
| AAAH | (6.9 ± 1.1) × 107 |
| Quadruple mutant | |
| AAAA | (9.8 ± 0.8) × 107 |
The inoculating virus dose was 6.5×103 to 1.2×104 PFU/egg.
PFU/milliliter at 48 h postinoculation.
