TABLE 2.

Vaccine-induced cellular immune responses do not affect the number of low-dose intrarectal challenges required for infection with SIVmac239^a

Vaccinated or control animal	No. of challenges
Vaccinees
r00014	3
r00044	6
r00060	7
r01008	6
r96133	4
r97111	2
r97113	7
r01080	4
Avg	4.88
Geometric mean	4.50
Controls
r98059	7
r99034	2
r99084	3
r00041	8
r00045	3
r00021	3
r01034	5
r98050	6
Avg	4.63
Geometric mean	4.17

^aAnimals were challenged intrarectally with 300 TCID₅₀ of SIVmac239. One week later, plasma was analyzed for viral concentration, and the animal was rechallenged while awaiting the results of the viral concentration determination. The date of infection was considered to be 7 days prior to the first positive viral concentration, and the number of challenges was considered to be how many had occurred, including the one on this date.