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. 2006 Jun;80(12):6155–6164. doi: 10.1128/JVI.00093-06

TABLE 3.

Cross-neutralizing activity against heterologous virus, determined by using plasma from antiretroviral-untreated subjectsa

Source of virus Neutralizing antibody titer from plasma fromb:
Virologic controller patient
Virologic noncontroller patient
1504 1508 1516c 1002 1006 1008 1017 1048 1512 1515 3018
Patient groups and ID no.
    Controllers
        1504 72 82 45 196* 375* 264* 117* 212* 397* 57 101
        1508 88* 83 83* 118* 130* 118* 107* 105* 498* 33 103
    Noncontrollers
        1002 51 67 37 94* 118* 37 51 80* 211* 46
        1006 57 99 71* 158* 57 177* 100* 143* 251* 30 50
        1008 123* 100 64* 117* 395* 52 68* 114* 192* 33 92
        1017 244* 175* 64* 388* 137* 175* 105* 1,119* 175* 425* 114
        1048 93* 92 35 131* 350* 64* 95* 102* 573* 50 86
        1512 57 56 32 114* 49 55 42 97* 140 33 77
        1515 91* 249* 69* 367* 122* 89* 57 310* 615* 41 139
        3018 103* 140 81* 249* 266* 187* 153* 198* 1,272* 77* 107
    PCAT
        2004 39 89 47 56 47 48 48 79* 1,195* 37 81
        3002 61 82 58 98* 165* 75* 40 152* 245* 38 78
        3037 129* 156 95* 418* 820* 154* 176* 373* 864* 118* 81
        3039 56 54 26 229* 153* 55 41 83* 144 43 95
Virus and lab strains
    JR-CSF 102 116 75 390 546 182 117 613 314 42 108
    NL4-3 4,713 1,720 906 1,891 2,058 639 3,702 5,043 1,950 1,366 781
    aMLV 24 58 20 31 26 20 20 22 50 20 65
a

Neutralizing HIV antibody titers were measured in plasma derived from chronically infected, antiretroviral drug-untreated subjects meeting our study definition of virologic controllers or noncontrollers (patient identification [ID] numbers are given). Neutralization titers were measured against a panel of heterologous primary viruses representing all three subject groups (virologic controllers, virologic noncontrollers, and PCAT).

b

See footnote b of Table 2 for explanations of neutralizing antibody titer, asterisks, and boldface type.

c

Virus could not be amplified for subject 1516.