Table 2.
Baseline Characteristics by Treatment Group*
|
Participants Who Received |
|||
|---|---|---|---|
| Participant Characteristics | No Antioxidants, % (n = 2310) | Antioxidants, % (n = 2286) | Total, % (n = 4596) |
| Age, y | |||
| 55–64 | 22 | 24 | 23 |
| 65–74 | 63 | 63 | 63 |
| 75–80 | 14 | 13 | 14 |
| Median | 69 | 68 | 68 |
| Female | 56 | 55 | 56 |
| Race | |||
| White | 96 | 96 | 96 |
| Black | 4 | 4 | 4 |
| Other | < 1 | < 1 | < 1 |
| AMD Category | |||
| 1 and 2 | 48 | 46 | 47 |
| 3 | 33 | 34 | 34 |
| 4 | 19 | 20 | 19 |
| Nuclear opacity score | |||
| < 2.0 | 35 | 39 | 37 |
| 2.0–3.9 | 49 | 47 | 48 |
| ≥ 4.0 | 15 | 15 | 15 |
| Cortical opacity, % of area | |||
| < 0.1 | 47 | 49 | 48 |
| 0.1–4.9 | 42 | 40 | 41 |
| ≥5.0 | 12 | 11 | 11 |
| PCS opacity, % of area | |||
| < 0.1 | 90 | 90 | 90 |
| 0.1–4.9 | 8 | 7 | 8 |
| ≥5.0 | 2 | 2 | 2 |
| Currently smoking | 7 | 8 | 8 |
| Former smoker | 48 | 47 | 48 |
| Chose to take Centrum at enrollment† | 67 | 65 | 66 |
| Taking multivitamins or a supplement containing a study medication | 56 | 54 | 55 |
| Taking insulin or pills for diabetes mellitus | 6 | 6 | 6 |
| Taking medication to control cholesterol and/or lipid levels | 9 | 9 | 9 |
| Taking aspirin | 40 | 37 | 38 |
| Taking antacids | 12 | 11 | 11 |
| Taking medication for hypertension | 32 | 32 | 32 |
| Diagnosis of angina | 10 | 10 | 10 |
| Prior diagnosis of cancer | 18 | 18 | 18 |
*
Data are given as a percentage unless otherwise indicated for all participants with follow-up information. AMD indicates age-related macular degeneration; PSC, posterior subcapsular.
†
The multivitamin and mineral supplement was Centrum (Whitehall-Robins Healthcare, Madison, NJ).