Table 7.
Five-Year Rates of Advanced AMD and (for Eyes That Did Not Progress to Advanced AMD) Rates of Progression From Scale Steps 1 to 6 to Step 7 or 8 or to Step 9, for Right and Left Eyes Combined, of Participants Free of Advanced AMD in Both Eyes at Baseline
|
No. (%) |
||||||
|---|---|---|---|---|---|---|
| Step | No. at Risk | Step 7 or 8 | Step 9 | NeoAMD | CGA | N + C |
| 1 | 2893 | 11 (0.4) | 4 (0.1) | 8 (0.3) | 0 | 0 |
| 2 | 899 | 21 (2.3) | 7 (0.8) | 5 (0.6) | 0 | 0 |
| 3 | 378 | 12 (3.2) | 3 (0.8) | 7 (1.9) | 0 | 0 |
| 4 | 653 | 90 (13.8) | 19 (2.9) | 28 (4.3) | 3 (0.5) | 1 (0.2) |
| 5 | 380 | 118 (31.1) | 24 (6.3) | 20 (5.3) | 2 (0.5) | 1 (0.3) |
| 6 | 483 | 249 (51.6) | 40 (8.3) | 54 (11.2) | 10 (2.1) | 3 (0.6) |
| 7 | 488 | NA | 93 (19.1) | 64 (13.1) | 61 (12.5) | 12 (2.5) |
| 8 | 190 | NA | 37 (19.5) | 40 (21.1) | 39 (20.5) | 11 (5.8) |
| 9 | 62 | NA | NA | 3 (4.8) | 27 (43.5) | 3 (4.8) |
| Total | 6426 | 501 (7.8) | 227 (3.5) | 229 (3.6) | 142 (2.2) | 31 (0.5) |
Abbreviations: AMD, age-related macular degeneration; CGA, geographic atrophy involving center of macula; NA, not applicable; NeoAMD, neovascular AMD; N + C, NeoAMD + CGA.