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. 2004;6(Suppl 4):S3–S8.

Figure 1.

Figure 1

Prostate cancer disease states. Diagram showing the clinical states in prostate cancer progressing from the suspected diagnosis of the disease based on evidence from prostate-specific antigen (PSA) levels or digital rectal examination (DRE) to death from either cancer or another cause, with the roles of salvage and novel therapies (Rx) indicated. Adapted with permission from Scher HI, Heller G. Clinical states in prostate cancer: toward a dynamic model of disease progression. Urology. 2000;55:323–327.