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. 2004;6(Suppl 9):S31–S39.

Figure 1.

Figure 1

The 2 5α-reductase inhibitors (5ARIs), dutasteride and finasteride, suppress dihydrotestosterone (DHT) by inhibiting the conversion of testosterone to DHT. Finasteride inhibits only the Type 2 5AR isoenzyme, whereas dutasteride, the only dual 5ARI, selectively inhibits both Type 1 and Type 2 5AR isoenzymes. Data from Bartsch G et al.1