Figure 5.

Photomicrographs of prostatic epithelium from men with benign prostatic hyperplasia before (above) and after (below) treatments that deprive the prostate of androgenic stimuli. On the left (black/white) are sections from Huggins’ patients circa 1940; treatment was castration. On the right (color) are sections from a contemporary treatment circa 1999: finasteride. The prostate tissue effect from the 2 treatments is similar. Reprinted with permission from Marks LS et al.⁸