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. 2001 Jan 23;98(3):1188–1193. doi: 10.1073/pnas.021558898

Figure 2.

Figure 2

Dicoumarol-induced p53 decrease occurs by proteasomal degradation. (A) HCT116 cells were incubated without (−) or with 200 and 400 μM dicoumarol and without (−) or with 100 μM MG 132 for 4 h. (B) HCT116 cells were incubated without (−) or with 400 μM dicoumarol without (−) or with 40 μM lactcystin for 4 h. Dic., dicoumarol.