TABLE 1.

Haplotype weighted analysis of PBEF T-1001G and T-1543C SNPs in patients with sepsis-associated ALI, sepsis and healthy controls

Haplotype*
Case	GT	GC	TT	TC	Total
Control	14.28	93.72	2.72	47.28	158
ALI	34.635	67.365	2.365	21.635	126
Sepsis	27.635	79.365	3.365	27.635	138
Total	76.55	240.45	8.45	96.55	422
χ2 test: p<0.01
Logistic regression analysis for the haplotype GT [Odds ratio (95% confidence interval)]
ALI	7.71 (3.01–19.75), P <0.001
Sepsis	4.84 (1.97–11.90), P = 0.001

All subjects are Caucasian. “Sepsis” denotes severe sepsis or septic shock.

^*T-1001G was genotyped by a RSP method while T-1543C was genotyped by an Assays-by-Design^SM Service-SNP Genotyping method (Applied Biosystems, CA). The sample size differences were due to the failure of the latter assays in some samples.

^*In each haplotype, first allele is from T-1001G and second allele from T-1543C.