Effects of MPA and DHT on TP receptor expression in female rhesus coronary VMC. A, TP receptor expression in primary coronary VMC from ovx RM treated for 72 h as follows: C, untreated control (lane 1); DHT10, DHT (10 nm) treatment (lane 2); DHT6, DHT (6 nm) treatment (lane 3); P, P (1 nm) treatment (lane 4); DHT6 ± MPA4, DHT (6 nm) and MPA (4 nm) treatment (lane 5); and MPA4, MPA (4 nm) treatment (lane 6). ERK1 detection was used as an internal loading control. B, Quantitation of TP receptor expression. Data are expressed as the mean ± sem and represent results from three independent experiments. *, P < 0.05; **, P < 0.05 (significant decrease compared with untreated control VMC).