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. 2001 Jan 30;98(3):1224–1229. doi: 10.1073/pnas.98.3.1224

Figure 4.

Figure 4

LCV infection in squirrel monkeys (Saimiri scireus) and phylogenetic relationship of LCVs and RVs in human and primates. (A) Herpesvirus DNA polymerase sequences detected in squirrel monkey PBLs. Degenerative oligonucleotide primer sets targeted to highly conserved regions of the herpesvirus DNA polymerase were used in nested PCR reactions with squirrel monkey PBL genomic DNA (5). The consensus sequence from a putative LCV in squirrel monkeys, Saimiriine herpesvirus-3, is shown at the top, and amino acid differences are shown for each clone sequenced from four animals. Conserved and missing amino acid residues are indicated by dots and dashes. Amino acid differences between animal 4, clone 2, and the RV Saimiriine herpesvirus-2 DNA polymerase sequence in GenBank (X64346) are underlined. (B) Phylogenetic relationship of LCVs from New World primates to other LCVs (EBV: V01555; baboon LCV: AF091051; rhesus LCV: AF091053) and RV (KSHV: U75698, HVS:X64346; RRV: 2625044; MHV-68: U97553). The New World primate LCVs are shown in italics.