Fig. 4.
Rb is not required for HSC self-renewal. (a) Secondary analysis of cells from the 1:1 primary transplant. Data represent the average percentage peripheral blood chimerism 9 weeks after transplantation, expressed as the mean ± SEM; n = 5 recipients per group. (b) Analysis of expression of Rb, p107, and p130 in isolated lin−c-Kit+Sca-1+ cells as analyzed by quantitative RT-PCR from secondary transplant recipients. n = 4 independent cDNA samples; data are expressed as means ± SEM.