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. 2006 Jun 5;103(24):9327–9332. doi: 10.1073/pnas.0603601103

Fig. 1.

Fig. 1.

Phase-shifting responses to light pulses in the circadian activity rhythms of C57BL/6J wild-type and Clock/+ mice. (A and B) Activity records of wild-type (A) and Clock/+ (B) mice given a 6-h light pulse at CT17. The arrow on the right margin indicates the day when the light pulse was given. Records are double-plotted so that 48 h are shown on each horizontal trace with a 24-h day presented beneath and to the right of the preceding day. Times of activity are indicated by dark regions. (C and D) Phase–response curve to 6-h light pulses in wild-type (n = 61) (C) and Clock/+ (n = 58) (D) mice. The x axis indicates the CT at the beginning of the light pulse. The y axis indicates the phase shift produced by the light pulse. (E and F) Phase–transition curve to the light pulses in wild-type (E) and Clock/+ (F) mice. Data from C and D are replotted so that the x axis indicates the phase (CT) at the beginning of the light pulse as determined from the preceding free run. The y axis indicates the extrapolated phase (CT) of the light pulse calculated from the reset rhythm.