Table 10. Concentrations of glutathione and glutathione disulfide in kidney.
2 mmol TRI/kg | 5 mmol TRI/kg | 15 mmol TRI/kg | ||||
---|---|---|---|---|---|---|
Male | Female | Male | Female | Male | Female | |
GSH | ||||||
2 hr | 941 ± 133a,f | 1023 ± 148a,f | 770 ± 215a,b | 1279 ± 186a,c | 848 ± 145a,f | 411 ± 105d,g |
4 hr | 691 ± 83b | 1141 ± 165a | 304 ± 55d,e | 880 ± 221a,b | 440 ± 49g | 156 ± 56h |
8 hr | 782 ± 97a,b | 1414 ± 126c | 365 ± 53d,g | 1408 ± 263c | 735 ± 145a,b | 102 ± 17h |
24 hr | 726 ± 200a,b | 1456 ± 186c | 265 ± 30e | 676 ± 218b,f,g | 283 ± 43e | 144 ± 32h |
48 hr | 751 ± 151a,b | 1547 ± 210c | 331 ± 42d | 907 ± 152a,b | 277 ± 45d,e | 170 ± 40h |
GSSG | ||||||
2 hr | < 22a | < 22a | < 22a | < 22a | < 22a | < 22a |
4 hr | < 22a | 29.7 ± 16.2a,b | < 22a | < 22a | < 22a | < 22a |
8 hr | < 22a | 55.0 ± 17.0b,c | < 22a | 76.7 ± 33.2b,c | < 22a | < 22a |
24 hr | < 22a | 22.7 ± 8.3a | < 22a | 78.7 ± 19.2c | < 22a | < 22a |
48 hr | < 22a | 47.0 ± 17.9b | < 22a | < 22a | < 22a | < 22a |
Values for either GSH or GSSG with different superscript letters are significantly different (P < 0.05) from one another.