Table 6. Distribution of CH, TCA, and TCOH in Kidney.
2 mmol TRI/kg | 5 mmol TRI/kg | 15 mmol TRI/kg | ||||
---|---|---|---|---|---|---|
Male | Female | Male | Female | Male | Female | |
CH | ||||||
2 hr | 0.47± 0.07a | 1.90 ± 0.39e | 0.31 ± 0.02h | 0.05 ± 0.02c | 0.92 ± 0.04b | < 0.05a |
4 hr | 0.77 ± 0.12b | 0.18 ± 0.04d,j | 2.42 ± 0.68e | < 0.05c | 1.26 ± 0.15g | 0.06 ± 0.02a,l |
8 hr | < 0.05c | 0.08 ± 0.02f,l | 4.18 ± 0.18i | 0.22 ± 0.03j | 0.32 ± 0.02h | 0.12 ± 0.03d,f |
24 hr | < 0.05c | 1.11 ± 0.02g | 2.34 ± 0.61e | 0.20 ± 0.10d,f,h,j | 0.41 ± 0.06a,h | 0.47 ± 0.01a,h |
48 hr | 0.15 ± 0.02d | 0.12 ± 0.04d,f | 4.32 ± 0.67i | 0.26 ± 0.10d,h,j | 0.38 ± 0.04a,h | < 0.05c |
TCA | ||||||
2 hr | 3.82 ± 1.32a,e,f | 17.3 ± 3.9c,h | 2.91 ± 0.14f | 7.44 ± 0.35b | 4.80 ± 0.67g | 30.1 ± 6.4i |
4 hr | 2.47 ± 0.17a | 13.7 ± 2.2c | 2.62 ± 0.64a,f | 8.63 ± 0.70b | 3.50 ± 0.11f | 15.5 ± 4.2c |
8 hr | 11.7 ± 4.0b,c | 35.9 ± 7.2d | 3.11 ± 0.11f | 6.74 ± 0.72b | 3.36 ± 0.23f | 14.4 ± 3.7c |
24 hr | 3.34 ± 0.67a,f | 4.27 ± 0.18e,g | 3.65 ± 0.77f,g | 21.6 ± 3.1h,i | 3.51 ± 0.16f | 6.76 ± 0.21b |
48 hr | 8.64 ± 1.30b | 19.1 ± 4.2c | 3.58 ± 0.25f | 13.8 ± 2.7c | 20.8 ± 6.1h,i | 7.65 ± 0.98b |
TCOH | ||||||
2 hr | < 0.05a | < 0.05a | < 0.05a | < 0.05a | 0.39 ± 0.06e | < 0.05a |
4 hr | < 0.05a | < 0.05a | 0.81 ± 0.29b | < 0.05a | 0.14 ± 0.01f | < 0.05a |
8 hr | < 0.05a | < 0.05a | 1.59 ± 0.16d | < 0.05a | 0.07± 0.01g | < 0.05a |
24 hr | < 0.05a | < 0.05a | 0.75 ± 0.30b | < 0.05a | 0.15 ± 0.01f | < 0.05a |
48 hr | < 0.05a | < 0.05a | 1.52 ± 0.39d | < 0.05a | 0.14 ± 0.01f | < 0.05a |
Values for a given metabolite with different superscript letters are significantly different (P < 0.05) from one another.