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. 2006 May 24;34(10):2847–2852. doi: 10.1093/nar/gkl355

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© The Author 2006. Published by Oxford University Press. All rights reserved

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The HsRad51 protein promotes joint molecule formation more efficiently with DNA containing three tandem telomeric repeat sequences (TTAGGG) than with the complement of this sequence. Joint molecules were formed with a 6-fold molar (molecule) excess of oligonucleotide relative to the homologous supercoiled plasmid. The percentage of joint molecule formation was determined relative to the limiting amount of plasmid DNA. The graph shows joint molecule formation promoted by HsRad51 protein with supercoiled plasmid DNA and homologous oligonucleotides containing the telomeric repeat sequence TTAGGG three times in tandem (TELO) as well as the complement of this sequence (TELO complement). Error bars represent the standard deviation.