Figure 5. Original mass spectrometric recordings of intact stripped colonic epithelium exposing the apical side to the reaction solution.

The inverted mucosal layer is slid over the Teflon cylinder as shown in Fig. 2. All experiments are in the presence of the extracellular CA inhibitor STAPTPP. A, proximal colon; B, distal colon. From these types of curve, the apical values of P_CO2 and P_HCO3 were calculated.