Table 3.

Effect of TRPV1 and CB₁ receptors antagonists on the NO production evoked by prototype vanilloid and cannabinoids agonists

	1 nm resiniferatoxin	100 nm anandamide	100 nm capsaicin
Untreated	134.8 ± 44.5 (4)	175.6 ± 13.9 (5)	93 ± 9.9 (6)
100 nm I-RTX	58.8 ± 10.9* (4)	8.2 ± 7.5** (4)	45.2 ± 13.5* (6)
100 nm SB 366791	52.7 ± 19.9* (4)	32.0 ± 19.9** (7)	29.3 ± 9.5** (4)
100 nm AM 251	142.2 ± 33.8 (4)	35.9 ± 11.2** (4)	119.5 ± 15.3 (4)
300 nm AM 251	124.8 ± 18.9 (2)	nd	43.5 ± 2.4* (2)

The data are ΔNO in pmol (means ±s.e.m.).

^*P < 0.05,

^**P < 0.01 as compared to the untreated tissues.