Table 2.
Control and 8br-cAMP open time constants
| mV | τlong (ms) | Along | τshort (ms) | Ashort | r | n | events |
|---|---|---|---|---|---|---|---|
| Control | |||||||
| −60 | 5.8 | 66% | 1.8 | 34% | 0.97 | 6 | 8768 |
| −70 | 10.5 | 39% | 2.3 | 61% | 0.97 | 8 | 17353 |
| −80 | 16.8 | 12% | 3.2 | 88% | 0.96 | 8 | 5350 |
| −90 | 19.3 | 23% | 3.0 | 77% | 0.91 | 6 | 3924 |
| −100 | 30.0 | 12% | 3.2 | 88% | 0.91 | 5 | 2052 |
| 8Br-cAMP | |||||||
| −30 | 85.2 | 9% | 18.6 | 91% | 0.68 | 3 | 858 |
| −40 | 26.7 | 32% | 9.5 | 68% | 0.75 | 4 | 748 |
| −50 | 43.5 | 36% | 10.3 | 64% | 0.63 | 3 | 416 |
| −60 | 44.3* | 25%* | 6.0* | 75%* | 0.71 | 6 | 673 |
| −70 | 27.2* | 24%* | 5.2* | 76%* | 0.90 | 4 | 2009 |
| −80 | n.d. | n.d. | |||||
| −90 | n.d. | n.d. | |||||
Open times were calculated from standard exponential fits of distribution histograms (bin width = 1 ms). Abbreviations: τ, time constant; A, area that τlong or τshort contributes to the exponential fit; r, correlation coefficient of exponential fit; n, number of patches; n.d., not determined. Voltages corrected for patch configuration. Significance was determined with unpaired t tests.
*
P≤ 0.001 versus control patches.